Introduction Investigating Pyrexia of Unknown Origin (PUO) requires a structured approach balancing non-invasive screening, advanced molecul...
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Temporal Arteritis (Giant Cell Arteritis) and Polymyalgia Rheumatica in Elderly PUO
Introduction Temporal Arteritis, also known as Giant Cell Arteritis (GCA), is a systemic vasculitis affecting medium and large-sized arterie...
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Drug Fever: Diagnostic Clues and Clinical Approach
Introduction Drug fever is an adverse drug reaction characterized by fever coinciding with the administration of a drug and disappearing aft...
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Approach to Tuberculosis as a Primary Cause of PUO
Tuberculosis (TB), caused by Mycobacterium tuberculosis , remains one of the leading infectious causes of Pyrexia of Unknown Origin worldwid...
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Adult-Onset Still’s Disease (AOSD): Diagnosis and Yamaguchi Criteria
Introduction Adult-Onset Still’s Disease (AOSD) is a rare systemic inflammatory disorder characterized by the classic triad of high spiking ...
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Understanding Infective Endocarditis: Diagnosis via Modified Duke Criteria
Introduction Infective Endocarditis (IE) is a life-threatening infection of the endocardial surface of the heart, most commonly affecting th...
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Clinical Evaluation and Management of Pyrexia of Unknown Origin (PUO)
Introduction Pyrexia of Unknown Origin (PUO) remains one of the most challenging diagnostic puzzles in clinical medicine . First defined by ...
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Clinical Evaluation & Classification of Soft Tissue Sarcomas: A Diagnostic Roadmap
Soft tissue sarcomas (STSs) represent a rare, highly heterogeneous group of malignant tumors originating from non-epithelial extraskeleta...
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