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What are the cutaneous signs of internal malignancy?

Intemal malignancy may have the following cutaneous maniesations
  • Acanthosis nigricans is seen in adenocarcinoma of GIT
  • Palmo-plantar keratoderma is the thick hard hyperkeratotic skin seen in carcinoma bronchus and oesophagus 
  • Necrolytic migratory erythema is seen in glucagonoma
  • Pityriasis rotunda seen in association with hepatocellular Carcinoma
  • Sign of Leser-Trelat is the sudden eruption of intensly pruritic multiple seborrhoeic keratosis in Carcinoma stomach
  • Migratory thrombophlebitis is a sign of Carcinoma  pancreas
  • Cutaneous hamartoma are seen in carcinaoma  breast, thyroid, gastrointestinal polyposis-cowdens disease
  • Pellagra like skin lesions are seen in Carcinoid syndrome
  • Pruritus is seen in association with Lymphoma, polycythemia vera
  • Dermatomyositis  can be seen in GI malignancy.