Intemal malignancy may have the following cutaneous maniesations
- Acanthosis nigricans is seen in adenocarcinoma of GIT
- Palmo-plantar keratoderma is the thick hard hyperkeratotic skin seen in carcinoma bronchus and oesophagus
- Necrolytic migratory erythema is seen in glucagonoma
- Pityriasis rotunda seen in association with hepatocellular Carcinoma
- Sign of Leser-Trelat is the sudden eruption of intensly pruritic multiple seborrhoeic keratosis in Carcinoma stomach
- Migratory thrombophlebitis is a sign of Carcinoma pancreas
- Cutaneous hamartoma are seen in carcinaoma breast, thyroid, gastrointestinal polyposis-cowdens disease
- Pellagra like skin lesions are seen in Carcinoid syndrome
- Pruritus is seen in association with Lymphoma, polycythemia vera
- Dermatomyositis can be seen in GI malignancy.
