It is the most common Migraine is the most common disabling primary headache globally.
12 percent of migraine are Episodic and 1 - 2 percentage is Chronic.Migraine Attacks are typically present with unilateral throbbing headache and it is associated with following symptoms
- Nausea
- Multisensory Hypersensitivity
- Marked fatigue.
The diverse symptomatology highlights the complexity of migraine as a whole nervous system disorder involving somatosensory, autonomic, endocrine, and arousal networks
Vascular Theory of Aura in Migrane
In Migraine there is Hereditary Susceptibility of Brain. There is Abnormal Intracranial and extra-cranial vascular reactivity to triggers. Aura is followed by Vasoconstriction, ischemia and focal neurological symptoms. Headache is due to Vasodilation and leads to pulsatile headache
What are the Pitfalls in Vascular theory
MRI perfusion study has showed that there is focal hyperemia precedes oligemia during Migraine aura. Perfusion abnormalities need not always match with symptoms of migraine. Oligemia may spread at 3mm/min beyond vascular territory. Headache can occur as that of migraine aura. Vascular theory cannot explain the premonitory phase. There wont be any Diffusion restriction in MRI doesn’t show
