CSF examination is done in the following situations
- Infections: meningitis, encephalitis
- Inflammatory conditions : Sarcoidosis, neuro syphilis, SLE
- Infiltrative conditions: Leukamia, lymphoma, carcinomatous - meningitis
- Administration of drugs in CSF (Therapeutic aim)
- Antibiotics: To give antibiotics in case of meningitis
- Antimitotics administation
- Diagnostic aim: Myelography, Cisternography
Contra-indications for Lumbar puncture
- Local skin infection over proposed puncture site is an absolute contraindication for LP
- Raised intracranial pressure (ICP), exception to this situation is pseudotumor cerebri
- If there is a suspicion of spinal cord mass or intracranial mass lesion (based on lateralizing neurological findings or papilledema)
- Uncontrolled bleeding disorders
- Spinal column deformities (may require fluoroscopic assistance)
- Lack of patient cooperation.