There are several neurological diseases that are associated with the corpus striatum, including:
1. Parkinson's disease: Parkinson's disease is a neurodegenerative disorder that affects movement control. It is characterized by the loss of dopamine-producing neurons in the substantia nigra, which leads to dysfunction in the nigrostriatal pathway that supplies dopamine to the striatum. This dysfunction in the striatum contributes to the motor symptoms of Parkinson's disease, including tremors, rigidity, and bradykinesia.
2. Huntington's disease: Huntington's disease is a genetic disorder that causes the progressive degeneration of the striatum, particularly the caudate nucleus. This results in a range of symptoms, including involuntary movements, cognitive decline, and behavioral changes.
3. Dystonia: Dystonia is a movement disorder that is characterized by involuntary muscle contractions that cause repetitive or twisting movements. It is often caused by dysfunction in the basal ganglia, including the striatum.
4. Tourette syndrome: Tourette syndrome is a neuropsychiatric disorder that is characterized by the presence of multiple motor and vocal tics. It is believed to be caused by dysfunction in the basal ganglia, including the striatum.
5. Obsessive-compulsive disorder (OCD): OCD is a mental disorder that is characterized by the presence of obsessive and/or compulsive behaviors. Dysfunction in the cortico-striatal-thalamo-cortical (CSTC) circuit, which involves the striatum, is believed to play a role in the development of OCD.
