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Function and disease of Neoerebellum

The neocerebellum, also known as the cerebrocerebellum, is involved in the planning and execution of voluntary movements. It receives input from the cerebral cortex via the pontine nuclei and sends output to the thalamus and cerebral cortex via the dentate nucleus and superior cerebellar peduncle, respectively. The neocerebellum plays a critical role in the coordination of complex movements, such as those involved in speech, writing, and playing musical instruments.

Dysfunction of the neocerebellum can lead to a variety of neurological disorders, including:

Ataxia: Ataxia is a lack of coordination or control of voluntary movements. It can result from damage to the neocerebellum or other areas of the cerebellum, and it can cause problems with balance, posture, and fine motor control.

Dysmetria: Dysmetria is a lack of coordination of movements that results in over- or undershooting a target. It can result from dysfunction of the neocerebellum or other areas of the cerebellum, and it can cause problems with fine motor control.

Dysarthria: Dysarthria is a speech disorder that results from weakness or incoordination of the muscles used in speech. It can result from dysfunction of the neocerebellum or other areas of the brain that are involved in speech production.

Intention tremor: Intention tremor is a type of tremor that occurs during purposeful movement, such as reaching for an object. It can result from dysfunction of the neocerebellum or other areas of the cerebellum that are involved in coordinating movements.

Hypotonia: Hypotonia is a decrease in muscle tone that can result from dysfunction of the neocerebellum or other areas of the brain that are involved in regulating muscle tone.

Overall, the neocerebellum is critical for the planning and execution of complex voluntary movements, and dysfunction of this part of the cerebellum can lead to a variety of neurological disorders that affect movement, coordination, and speech.