Mitral regurgitation can occur secondary to lesion of mitral annulus, chordac, papillary muscle, left ventricular lesions.
Caspal lesions
- Rheumatoid heart disease
- Mild valve pro-lapse
- Infective endocarditis
- Trauma
Annular lesions
- Dilatation of annulus – Dilated cardiomyopathy ,Ischemic heart disease
- Annular calcification
Chordal lesions
- Mitral valve prolapse
- Infective endocarditis
- Trauma
Papillary muscle dysfunction
- Myocardial infarction
- Angina
Left ventricular lesions
- Aneurysm
- Hypertrophic cardiomyopathy
Connective tissue diseases associated with mitral regurgitations are
- Marfan syndrome
- Ehler Danlos syndrome
- Rheumatoid arthritis
