Drug fever has the following clinical features.
- Drug induced fever is a prolonged fever and it may belong to any febrile pattern given below
- There is relative bradycardia and hypotension associated with this fever
- Pruritus, skin rash and arthralgia can occur
- It begins 1-3 weeks after the start of the drugs and this may persists 2-3 day's after the drug is stopped
- .Eosinophilia may be present.
Agents causing drug fever
- Sulphonamides.
- Iodides, bromides.
- Thiouracils.
- Barbiturates.
- Rifampicin (‘flu syndrome’)
- Phenolpthalein (used in laxatives).
- Quinidine.
- Phenytoin
