Following are the clinical feaatures of hemolytic jaundice
- Acholuric urine means freshly passed urine is of normal colour as there is no bilirubin in urine but if the urine sample is kept for sometime, this will turn dark yellow due to conversion of urobilinogen to urobilin by oxidation.
- Stool is high-coloured due to excess amount of stercobilinogen and stercobilin.
- Jaundice is usually mild and there is lemon-yellow tinge of bulbarconjunctlva.
- Serum bilirubin is usually less than 6 mg/dl and this is predominantly of unconjugaled variety.
- Anaemia is present .It can be mild, moderate or severe, according to the degree of haemolytic process.
- Splenomegaly, is very characteristic of haemolytic anemia
Following are the common causes of haemolytic jaundice
- Thalassaemia.
- Mismatched blood transfusion.
- Snake bite (Viperidae group).
- Malaria (specially falciparum malaria).
- Rh incompatibility.
- Primaquine or sulphonamide-induced (in GePD deficiency).
